Schizoaffective Disorder

Difference Between Schizoaffective Disorder and Mood Disorders

What is the difference in clinical presentation between schizoaffective disorder and mood disorder with psychotic features?

In clinical practice, as opposed to psychiatric textbooks, there is often very little difference in presentation between schizoaffective disorder (SD) and a mood disorder with psychotic features (MDPF). The trick is in sorting out the "longitudinal course" of the illness over a period of months or years. By definition, SD individuals must show a period of time during which they meet criteria for both the "A" symptoms of schizophrenia (delusions, hallucinations) AND either a manic or major depressive episode. In addition, SD patients must show a "disconnect" - a period of at least two weeks in which they have psychotic features (delusions or hallucinations) without any prominent mood symptoms.

In practice, it is often difficult to sort out such meticulous details, since most people who are becoming psychotic do not keep careful notes on the course of their symptoms! Very often, we rely on family or spouse to help us make the diagnosis.

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In theory, someone with MDPF (mood disorder with psychotic features) usually experiences mood and psychotic features simultaneously, with both types of symptoms coming and going over roughly the same time period. But, in fact, it is not always so clear, since some people begin with a non-psychotic depressive or manic episode and eventually develop delusional features. Generally, though, MDPF patients do not have prolonged delusional periods without mood symptoms.

There is also a good deal of heterogeneity in the Schizoaffective Disorder category, with bipolar-type Schizoaffective Disorder patients often resembling classic bipolar individuals and depressive-type SD patients looking more like MDPF patients.

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